IL-1 beta, human recombinant
Details
Recombinant
Yes
Concentration
N/A
Activity (Specifications/test method)
N/A
NCBI Gene ID #.
3553
NCBI Gene Symbol
IL1B
Gene Source
Human
Accession #
P01584
Purity
≥98%
Shelf Life
1 year
Storage Temp.
-20°C
Source
E. coli
Molecular Weight
17.0 kDa
Shipping
Gel pack
Biomolecule/Target
IL-1 beta
Group
recombinants
Appearance
Lyophilized protein
Additional source
Recombinants or rec. proteins
Physical form description
Lyophilized with no additives.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Taglines
An important mediator of inflammatory responses
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by murine C3H/HeJ thymocytes is 1 x 10⁷ units/mg.
Alternates names
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Synonyms
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Reconstitution Instructions
We recommend a quick spin followed by reconstitution in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or stored at –20°C for future use.
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.