IL-1 beta, rat recombinant
Details
Gene Source
Rat
Recombinant
Yes
Activity (Specifications/test method)
N/A
Concentration
N/A
NCBI Gene Symbol
IL1B
Storage Temp.
-20°C
Accession #
Q63264
Purity
≥98%
Shelf Life
1 year
Source
E. coli
Molecular Weight
17.3 kDa
Shipping
Gel pack
Biomolecule/Target
IL-1 beta
Group
recombinants
NCBI Gene ID #.
UniGene:Rn.9869
Latin name
Rattus norvegicus
Appearance
Lyophilized protein
Additional source
Recombinants or rec. proteins
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Taglines
An important mediator of inflammatory responses
Physical form description
Sterile filtered and then lyophilized from 10 mM Sodium Acetate, pH 6.5
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is 1 x 10⁷ units/mg.
Alternates names
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Synonyms
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week or –20°C for future use.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.