IL-1 RA, human recombinant
Details
Recombinant
Yes
Concentration
N/A
Endotoxin Level
N/A
Activity (Specifications/test method)
N/A
NCBI Gene ID #.
3557
Gene Source
Human
NCBI Gene Symbol
IL-1RA
Accession #
P18510
Purity
≥98%
Shelf Life
1 year
Storage Temp.
-20°C
Biomolecule/Target
IL-1 RA
Source
E. coli
Shipping
Blue ice
Molecular Weight
17.0 kDa
Results
0.5 ng/ml.
Group
recombinants
Appearance
Lyophilized protein
Physical form description
Lyophilized without additves
Additional source
Recombinants or rec. proteins
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Taglines
A natural inhibitor of the pro-inflammatory effect of IL1β
Alternates names
IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430
Synonyms
IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430
Biological activity
The ED₅₀ as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells was found to be 0.5 ng/ml.
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers.
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.