anti-IL-1 alpha Antibody, Monoclonal
Details
NCBI GENE nr
3552
GENE symbol
IL1A
Ab raised in
Mouse
Immunoglobulin
IgG2a
Works with
Human
Omim nr
124297
Ncbi nr
P01583
Protein nr
P01583
French translation
anticorps
Type
Monoclonal
Vial with antibody
in solution
Source
Homo sapiens
Antibodie's label
unlabelled serum
Purity
Protein A Column
Antigene name
interleukin 1, alpha
Suspention, pH, azide
PBS, pH 7.4, 0.03% sodium azide.
Immuno application
ELISA, Western Blot, immuno-histo-chemistry
Antibody advice
IL-1 alpha antibody can be used in ELISA, and immunohistochemistry starting at 20 ug/mL.
Keep at
Store IL-1 alpha antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
Antigen
IL - 1 alpha monoclonal antibody was made against Ni-NTA purified recombinant human IL-1alpha expressed in E. Coli strain BL21 (DE3)
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Gene names
IL1A, Hematopoietin-1, IL-1 alpha, IL1, IL1-ALPHA, IL1 Alpha, Interleukin-1 alpha, IL-1A, IL1F1, Pro-interleukin-1-alpha, Preinterleukin 1 alpha, Interleukin 1, alpha
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
Description
The anti-IL-1 alpha Antibody, Monoclonal is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Gene info
Interleukin 1 alpha is synthesized as a 31 kDa promolecule that does not contain a signal sequence. Following proteolytic cleavage, the mature 17 kDa molecule is released as a result of cell injury or apoptosis. IL-1 alpha stimulates bone osteoclast activity, has a role in the modulation of extracellular fluid calcium homeostasis and apoptosis, activates T and B lymphocytes and NK cells, and functions in development. Movement of the IL-1 alpha promolecule to the nucleus in response to endotoxin where it augments transcription of proinflammatory genes has also been documented.