IL-1 alpha, human recombinant
Details
Recombinant
Yes
Activity (Specifications/test method)
N/A
Concentration
N/A
NCBI Gene ID #.
3552
NCBI Gene Symbol
IL1A
Gene Source
Human
Storage Temp.
-20°C
Accession #
P01583
Purity
≥98%
Shelf Life
1 year
Source
E. coli
Shipping
Gel pack
Molecular Weight
18.0 kDa
Biomolecule/Target
IL-1 alpha
Group
recombinants
Appearance
Lyophilized protein
Additional source
Recombinants or rec. proteins
Handling
Centrifuge the vial prior to opening.
Physical form description
Sterile filtered and lyophilized powder
Usage
For Research Use Only! Not to be used in humans
Taglines
Activates TNF-α and plays a critical role in immune response regulation
Description
The IL-1 alpha, recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is 1 x 10⁹ units/mg.
Alternates names
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Synonyms
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.