Details

Recombinant

Yes

Activity (Specifications/test method)

N/A

Concentration

N/A

 

NCBI Gene ID #.

3552

NCBI Gene Symbol

IL1A

Gene Source

Human

 

Storage Temp.

-20°C

Accession #

P01583

Purity

≥98%

 

Shelf Life

1 year

Source

E. coli

Shipping

Gel pack

 

Molecular Weight

18.0 kDa

Biomolecule/Target

IL-1 alpha

Group

recombinants

 

Appearance

Lyophilized protein

Additional source

Recombinants or rec. proteins

Handling

Centrifuge the vial prior to opening.

 

Physical form description

Sterile filtered and lyophilized powder

Usage

For Research Use Only! Not to be used in humans

Taglines

Activates TNF-α and plays a critical role in immune response regulation

 

Description

The IL-1 alpha, recombinant is a α- or alpha protein sometimes glycoprotein present in blood.

Biological activity

The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is 1 x 10⁹units/mg.

Alternates names

Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

 

Synonyms

Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Reconstitution Instructions

Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

 

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.