Details

Gene Source

Rat

Recombinant

Yes

Activity (Specifications/test method)

N/A

 

Concentration

N/A

NCBI Gene Symbol

IL1A

NCBI Gene ID #.

24493

 

Storage Temp.

-20°C

Accession #

P16598

Purity

≥98%

 

Shelf Life

1 year

Source

E. coli

Molecular Weight

17.7 kDa

 

Shipping

Gel pack

Biomolecule/Target

IL-1 alpha

Group

recombinants

 

Latin name

Rattus norvegicus

Appearance

Lyophilized protein

Additional source

Recombinants or rec. proteins

 

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Physical form description

Sterile filtered and lyophilized from 1 mM Tris buffer, pH 8.0

 

Taglines

Activates TNF-α and plays a critical role in immune response regulation

Description

The IL-1 alpha, recombinant is a α- or alpha protein sometimes glycoprotein present in blood.

Biological activity

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is 2 x 10⁹ units/mg.

 

Alternates names

Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Synonyms

Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Reconstitution Instructions

Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

 

About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.