IL-1 alpha, rat recombinant
Details
Gene Source
Rat
Recombinant
Yes
Activity (Specifications/test method)
N/A
Concentration
N/A
NCBI Gene Symbol
IL1A
NCBI Gene ID #.
24493
Storage Temp.
-20°C
Accession #
P16598
Purity
≥98%
Shelf Life
1 year
Source
E. coli
Molecular Weight
17.7 kDa
Shipping
Gel pack
Biomolecule/Target
IL-1 alpha
Group
recombinants
Latin name
Rattus norvegicus
Appearance
Lyophilized protein
Additional source
Recombinants or rec. proteins
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Physical form description
Sterile filtered and lyophilized from 1 mM Tris buffer, pH 8.0
Taglines
Activates TNF-α and plays a critical role in immune response regulation
Description
The IL-1 alpha, recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is 2 x 10⁹ units/mg.
Alternates names
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Synonyms
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Gene
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.