Details

Recombinant

Yes

Concentration

N/A

Activity (Specifications/test method)

N/A

 

NCBI Gene ID #.

3553

NCBI Gene Symbol

IL1B

Gene Source

Human

 

Accession #

P01584

Purity

≥98%

Shelf Life

1 year

 

Storage Temp.

-20°C

Source

E. coli

Molecular Weight

17.0 kDa

 

Shipping

Gel pack

Biomolecule/Target

IL-1 beta

Group

recombinants

 

Appearance

Lyophilized protein

Additional source

Recombinants or rec. proteins

Physical form description

Lyophilized with no additives.

 

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Taglines

An important mediator of inflammatory responses

 

Biological activity

The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by murine C3H/HeJ thymocytes is 1 x 10⁷ units/mg.

Alternates names

Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Synonyms

Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

 

Reconstitution Instructions

We recommend a quick spin followed by reconstitution in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or stored at –20°C for future use.

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.