Details

Gene Source

Rat

Recombinant

Yes

Activity (Specifications/test method)

N/A

 

Concentration

N/A

NCBI Gene Symbol

IL1B

Storage Temp.

-20°C

 

Accession #

Q63264

Purity

≥98%

Shelf Life

1 year

 

Source

E. coli

Molecular Weight

17.3 kDa

Shipping

Gel pack

 

Biomolecule/Target

IL-1 beta

Group

recombinants

NCBI Gene ID #.

UniGene:Rn.9869

 

Latin name

Rattus norvegicus

Appearance

Lyophilized protein

Additional source

Recombinants or rec. proteins

 

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Taglines

An important mediator of inflammatory responses

 

Physical form description

Sterile filtered and then lyophilized from 10 mM Sodium Acetate, pH 6.5

Biological activity

The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is 1 x 10⁷ units/mg.

Alternates names

Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

 

Synonyms

Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Reconstitution Instructions

Centrifuge the vial prior to opening. Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week or –20°C for future use.

About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

 

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.