Details

Recombinant

Yes

Concentration

N/A

Endotoxin Level

N/A

 

Activity (Specifications/test method)

N/A

NCBI Gene ID #.

3557

Gene Source

Human

 

NCBI Gene Symbol

IL-1RA

Accession #

P18510

Purity

≥98%

 

Shelf Life

1 year

Storage Temp.

-20°C

Biomolecule/Target

IL-1 RA

 

Source

E. coli

Shipping

Blue ice

Molecular Weight

17.0 kDa

 

Results

0.5 ng/ml.

Group

recombinants

Appearance

Lyophilized protein

 

Physical form description

Lyophilized without additves

Additional source

Recombinants or rec. proteins

Handling

Centrifuge the vial prior to opening.

 

Usage

For Research Use Only! Not to be used in humans

Taglines

A natural inhibitor of the pro-inflammatory effect of IL1β

Alternates names

IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430

 

Synonyms

IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430

Biological activity

The ED₅₀ as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells was found to be 0.5 ng/ml.

Reconstitution Instructions

Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers.

 

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.