Details

NCBI GENE nr

3552

GENE symbol

IL1A

Ab raised in

Mouse

 

Immunoglobulin

IgG2a

Works with

Human

Omim nr

124297

 

Ncbi nr

P01583

Protein nr

P01583

French translation

anticorps

 

Type

Monoclonal

Vial with antibody

in solution

Source

Homo sapiens

 

Antibodie's label

unlabelled serum

Purity

Protein A Column

Antigene name

interleukin 1, alpha

 

Suspention, pH, azide

PBS, pH 7.4, 0.03% sodium azide.

Immuno application

ELISA, Western Blot, immuno-histo-chemistry

Antibody advice

IL-1 alpha antibody can be used in ELISA, and immunohistochemistry starting at 20 ug/mL.

 

Keep at

Store IL-1 alpha antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.

Antigen

IL - 1 alpha monoclonal antibody was made against Ni-NTA purified recombinant human IL-1alpha expressed in E. Coli strain BL21 (DE3)

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

 

Gene names

IL1A, Hematopoietin-1, IL-1 alpha, IL1, IL1-ALPHA, IL1 Alpha, Interleukin-1 alpha, IL-1A, IL1F1, Pro-interleukin-1-alpha, Preinterleukin 1 alpha, Interleukin 1, alpha

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

Description

The anti-IL-1 alpha Antibody, Monoclonal is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

 

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Gene info

Interleukin 1 alpha is synthesized as a 31 kDa promolecule that does not contain a signal sequence. Following proteolytic cleavage, the mature 17 kDa molecule is released as a result of cell injury or apoptosis. IL-1 alpha stimulates bone osteoclast activity, has a role in the modulation of extracellular fluid calcium homeostasis and apoptosis, activates T and B lymphocytes and NK cells, and functions in development. Movement of the IL-1 alpha promolecule to the nucleus in response to endotoxin where it augments transcription of proinflammatory genes has also been documented.