Details

Concentration

N/A

Immunoglobulin isotype

IgG2a

Clone

10K61

 

Also known as

SIGIRR

Category

Antibodies

Clonality

Monoclonal

 

Subcategory

Mnoclonal antibodies

Source organism

Human (Homo sapiens)

Host organism

Mouse (Mus musculus)

 

Tested applications:

Flow Cytometry (FC/FACS)

Other gene names

SIGIRR; SIGIRR; TIR8; MGC110992; N/A

Gene name synonims

SIGIRR; SIGIRR; TIR8; MGC110992; N/A

 

Gene name

SIGIRR; SIGIRR; TIR8; MGC110992; N/A

Purification method

Affinity Purified by Protein G affinity chromatography.

Form/Appearance

Supplied as a liquid in PBS, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).

 

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes human SIGIRR.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

 

Storage and shipping

May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius. as an undiluted liquid. Stable for 12 months. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.

Other names

single Ig IL-1-related receptor; Single Ig IL-1-related receptor; single Ig IL-1-related receptor; OTTHUMP00000229641; OTTHUMP00000229642; OTTHUMP00000229643; OTTHUMP00000229644; OTTHUMP00000229645; toll/interleukin-1 receptor 8; single Ig IL-1R-related molecule; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; Single Ig IL-1R-related molecule; Single immunoglobulin domain-containing IL1R-related protein; Toll/interleukin-1 receptor 8

Description

Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.