Details

Modification(s)

None

Gene ID number

16175

French translation

anticorps

 

Target Antigen

IL-1 Alpha

Cross reactivity

Mouse, Rat

Concentration

1ug per 1ul

 

Conjugation

Unconjugated

Also known as

IL-1 Alpha PAb

Category

Primary Antibodies

 

Modification site(s)

Unmodified antibody

Clone number

Polyclonal antibody

Clonality

Polyclonal antibody

 

Tested Applications

WB, IHC-P, IF(IHC-P)

Long name

IL-1 Alpha Primary Polyclonal Antibody

Purification method

This antibody was purified via Protein A.

 

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Specificity

This is a highly specific antibody against IL-1 Alpha.

Source

KLH conjugated synthetic peptide derived from mouse IL-1 Alpha

 

Description

The Anti-IL-1 Alpha is a α- or alpha protein sometimes glycoprotein present in blood.

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

 

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonym names

interleukin-1 alpha; Hematopoietin 1; IL 1 alpha; IL 1; IL 1A; Il-1a; IL1; IL1A; IL1F1; ilia; Interleukin 1 alpha; Interleukin 1 alpha precursor; Interleukin1 alpha; Preinterleukin 1 alpha; Pro interleukin 1 alpha; Prointerleukin 1 alpha.

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

 

Background of the target antigen

Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin 1 alpha (IL1 alpha) and interleukin 1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.