Details

Uniprot #

P01583

Category

Antibody

Tested applications

WB, ELISA

 

French translation

anticorps

Recognised antigen

IL-1 alpha

Conjugation

Unconjugated

 

Purity

Antigen affinity

Clone

Polyclonal antibody

Recommended dilutions

Western blot: 1:1000

 

Form

Antigen affinity purified

Clonality

Polyclonal (rabbit origin)

Host animal

Rabbit (Oryctolagus cuniculus)

 

Concentration

In 1X PBS, pH 7.4, with 0.09% sodium azide

Additional description

The Anti-IL-1 alpha is a α- or alpha protein sometimes glycoprotein present in blood.

Intented use

This IL-1 alpha antibodyis to be used only for research purposes and not for diagnostics..

 

Immunogen

A portion of amino acids 65-94 from human IL1A was used as the immunogen for this IL-1 alpha antibody.

Notes

Titration of the IL-1 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Properties

If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

 

Species reactivity

Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.

Gene

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.

Storage

Aliquot the IL-1 alpha antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.

 

Description

IL1A is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis.